Other applications
Other applications
Other applications
Other applications
- Boron-neutron-capture therapy for cancer
- Radiation biotechnology
- Boron-neutron-capture therapy for cancer
- Radiation biotechnology
- Boron-neutron-capture therapy for cancer
- Radiation biotechnology
- Boron-neutron-capture therapy for cancer
- Radiation biotechnology
Boron-neutron-capture therapy for cancer
Boron-neutron-capture therapy is a promising technique of therapeutic treatment of malignant tumours by accumulation of stable isotope boron-10 in them and subsequent irradiation with neutrons. As a result of neutron absorption by boron, a nuclear reaction with a large release of energy occurs in the very cell that contained the boron nucleus, which leads to its death.
Our laboratory supplied a high-voltage ELV rectifier for BNCT in Xiamen, China, as well as for the Tandem facility created and developed at the Institute of Nuclear Physics of the Siberian Branch of the Russian Academy of Sciences.
Our laboratory supplied a high-voltage ELV rectifier for BNCT in Xiamen, China, as well as for the Tandem facility created and developed at the Institute of Nuclear Physics of the Siberian Branch of the Russian Academy of Sciences.
Boron-neutron-capture therapy is a promising technique of therapeutic treatment of malignant tumours by accumulation of stable isotope boron-10 in them and subsequent irradiation with neutrons. As a result of neutron absorption by boron, a nuclear reaction with a large release of energy occurs in the very cell that contained the boron nucleus, which leads to its death.
Our laboratory supplied a high-voltage ELV rectifier for BNCT in Xiamen, China, as well as for the Tandem facility created and developed at the Institute of Nuclear Physics of the Siberian Branch of the Russian Academy of Sciences.
Our laboratory supplied a high-voltage ELV rectifier for BNCT in Xiamen, China, as well as for the Tandem facility created and developed at the Institute of Nuclear Physics of the Siberian Branch of the Russian Academy of Sciences.
Boron-neutron-capture therapy for cancer
Schematic diagram of the ‘Tandem’ installation
High voltage rectifier ELV for BNCT in Xiamen, China.
Treatment of patients using the accelerating neutron source for boron-neutron-capture therapy (BNCT) for cancer is scheduled to begin in late 2025.
Treatment of patients using the accelerating neutron source for boron-neutron-capture therapy (BNCT) for cancer is scheduled to begin in late 2025.
Treatment of patients using the accelerating neutron source for boron-neutron-capture therapy (BNCT) for cancer is scheduled to begin in late 2025.
Treatment of patients using the accelerating neutron source for boron-neutron-capture therapy (BNCT) for cancer is scheduled to begin in late 2025.
Research and technological developments in the field of radiation biotechnology are carried out in two main directions: fabrication of biocompatible materials and immobilisation of bioactive substances in polymer matrices.
Synthetic polymers are often used as biomaterials. The main disadvantage of these polymers is the presence of toxic substances that can be leached into the aqueous biological environment. The main radiation method for obtaining biocompatible materials is graft polymerisation. This method is most often used to produce hydrogels, mainly based on polyacrylamide, polyvinyl alcohol and polyethylene oxide.
The advantage of radiation cross-linking is comparative simplicity of execution, possibility of wide regulation of mesh density by selection of irradiation conditions (dose rate, dose), possibility of using reduced temperatures, purity of the obtained product (absence of initiators) and simultaneous sterilisation. Radiation-crosslinked hydrogels are used as carriers of biologically active substances (enzymes, drugs, etc.), as implants, prostheses, eye lenses, medical membranes, dressing materials and biological media for the study and cultivation of microorganisms.
The alteration of the physical properties of materials (mainly solids) as a result of irradiation has provided the basis for several other practical applications. They include ion implantation (at ion accelerators), doping of semiconductors by nuclear reactions (under the action of thermal neutrons), modification of semiconductor materials and products, fabrication of polymer membranes and resistors for lithography, changing the colour of glass and crystals, thermal effect of powerful electron beams, etc.
Synthetic polymers are often used as biomaterials. The main disadvantage of these polymers is the presence of toxic substances that can be leached into the aqueous biological environment. The main radiation method for obtaining biocompatible materials is graft polymerisation. This method is most often used to produce hydrogels, mainly based on polyacrylamide, polyvinyl alcohol and polyethylene oxide.
The advantage of radiation cross-linking is comparative simplicity of execution, possibility of wide regulation of mesh density by selection of irradiation conditions (dose rate, dose), possibility of using reduced temperatures, purity of the obtained product (absence of initiators) and simultaneous sterilisation. Radiation-crosslinked hydrogels are used as carriers of biologically active substances (enzymes, drugs, etc.), as implants, prostheses, eye lenses, medical membranes, dressing materials and biological media for the study and cultivation of microorganisms.
The alteration of the physical properties of materials (mainly solids) as a result of irradiation has provided the basis for several other practical applications. They include ion implantation (at ion accelerators), doping of semiconductors by nuclear reactions (under the action of thermal neutrons), modification of semiconductor materials and products, fabrication of polymer membranes and resistors for lithography, changing the colour of glass and crystals, thermal effect of powerful electron beams, etc.
Research and technological developments in the field of radiation biotechnology are carried out in two main directions: fabrication of biocompatible materials and immobilisation of bioactive substances in polymer matrices.
Synthetic polymers are often used as biomaterials. The main disadvantage of these polymers is the presence of toxic substances that can be leached into the aqueous biological environment. The main radiation method for obtaining biocompatible materials is graft polymerisation. This method is most often used to produce hydrogels, mainly based on polyacrylamide, polyvinyl alcohol and polyethylene oxide.
The advantage of radiation cross-linking is comparative simplicity of execution, possibility of wide regulation of mesh density by selection of irradiation conditions (dose rate, dose), possibility of using reduced temperatures, purity of the obtained product (absence of initiators) and simultaneous sterilisation. Radiation-crosslinked hydrogels are used as carriers of biologically active substances (enzymes, drugs, etc.), as implants, prostheses, eye lenses, medical membranes, dressing materials and biological media for the study and cultivation of microorganisms.
The alteration of the physical properties of materials (mainly solids) as a result of irradiation has provided the basis for several other practical applications. They include ion implantation (at ion accelerators), doping of semiconductors by nuclear reactions (under the action of thermal neutrons), modification of semiconductor materials and products, fabrication of polymer membranes and resistors for lithography, changing the colour of glass and crystals, thermal effect of powerful electron beams, etc.
Synthetic polymers are often used as biomaterials. The main disadvantage of these polymers is the presence of toxic substances that can be leached into the aqueous biological environment. The main radiation method for obtaining biocompatible materials is graft polymerisation. This method is most often used to produce hydrogels, mainly based on polyacrylamide, polyvinyl alcohol and polyethylene oxide.
The advantage of radiation cross-linking is comparative simplicity of execution, possibility of wide regulation of mesh density by selection of irradiation conditions (dose rate, dose), possibility of using reduced temperatures, purity of the obtained product (absence of initiators) and simultaneous sterilisation. Radiation-crosslinked hydrogels are used as carriers of biologically active substances (enzymes, drugs, etc.), as implants, prostheses, eye lenses, medical membranes, dressing materials and biological media for the study and cultivation of microorganisms.
The alteration of the physical properties of materials (mainly solids) as a result of irradiation has provided the basis for several other practical applications. They include ion implantation (at ion accelerators), doping of semiconductors by nuclear reactions (under the action of thermal neutrons), modification of semiconductor materials and products, fabrication of polymer membranes and resistors for lithography, changing the colour of glass and crystals, thermal effect of powerful electron beams, etc.
Research and technological developments in the field of radiation biotechnology are carried out in two main directions: fabrication of biocompatible materials and immobilisation of bioactive substances in polymer matrices.
Synthetic polymers are often used as biomaterials. The main disadvantage of these polymers is the presence of toxic substances that can be leached into the aqueous biological environment. The main radiation method for obtaining biocompatible materials is graft polymerisation. This method is most often used to produce hydrogels, mainly based on polyacrylamide, polyvinyl alcohol and polyethylene oxide.
The advantage of radiation cross-linking is comparative simplicity of execution, possibility of wide regulation of mesh density by selection of irradiation conditions (dose rate, dose), possibility of using reduced temperatures, purity of the obtained product (absence of initiators) and simultaneous sterilisation. Radiation-crosslinked hydrogels are used as carriers of biologically active substances (enzymes, drugs, etc.), as implants, prostheses, eye lenses, medical membranes, dressing materials and biological media for the study and cultivation of microorganisms.
The alteration of the physical properties of materials (mainly solids) as a result of irradiation has provided the basis for several other practical applications. They include ion implantation (at ion accelerators), doping of semiconductors by nuclear reactions (under the action of thermal neutrons), modification of semiconductor materials and products, fabrication of polymer membranes and resistors for lithography, changing the colour of glass and crystals, thermal effect of powerful electron beams, etc.
Synthetic polymers are often used as biomaterials. The main disadvantage of these polymers is the presence of toxic substances that can be leached into the aqueous biological environment. The main radiation method for obtaining biocompatible materials is graft polymerisation. This method is most often used to produce hydrogels, mainly based on polyacrylamide, polyvinyl alcohol and polyethylene oxide.
The advantage of radiation cross-linking is comparative simplicity of execution, possibility of wide regulation of mesh density by selection of irradiation conditions (dose rate, dose), possibility of using reduced temperatures, purity of the obtained product (absence of initiators) and simultaneous sterilisation. Radiation-crosslinked hydrogels are used as carriers of biologically active substances (enzymes, drugs, etc.), as implants, prostheses, eye lenses, medical membranes, dressing materials and biological media for the study and cultivation of microorganisms.
The alteration of the physical properties of materials (mainly solids) as a result of irradiation has provided the basis for several other practical applications. They include ion implantation (at ion accelerators), doping of semiconductors by nuclear reactions (under the action of thermal neutrons), modification of semiconductor materials and products, fabrication of polymer membranes and resistors for lithography, changing the colour of glass and crystals, thermal effect of powerful electron beams, etc.
Research and technological developments in the field of radiation biotechnology are carried out in two main directions: fabrication of biocompatible materials and immobilisation of bioactive substances in polymer matrices.
Synthetic polymers are often used as biomaterials. The main disadvantage of these polymers is the presence of toxic substances that can be leached into the aqueous biological environment. The main radiation method for obtaining biocompatible materials is graft polymerisation. This method is most often used to produce hydrogels, mainly based on polyacrylamide, polyvinyl alcohol and polyethylene oxide.
The advantage of radiation cross-linking is comparative simplicity of execution, possibility of wide regulation of mesh density by selection of irradiation conditions (dose rate, dose), possibility of using reduced temperatures, purity of the obtained product (absence of initiators) and simultaneous sterilisation. Radiation-crosslinked hydrogels are used as carriers of biologically active substances (enzymes, drugs, etc.), as implants, prostheses, eye lenses, medical membranes, dressing materials and biological media for the study and cultivation of microorganisms.
The alteration of the physical properties of materials (mainly solids) as a result of irradiation has provided the basis for several other practical applications. They include ion implantation (at ion accelerators), doping of semiconductors by nuclear reactions (under the action of thermal neutrons), modification of semiconductor materials and products, fabrication of polymer membranes and resistors for lithography, changing the colour of glass and crystals, thermal effect of powerful electron beams, etc.
Synthetic polymers are often used as biomaterials. The main disadvantage of these polymers is the presence of toxic substances that can be leached into the aqueous biological environment. The main radiation method for obtaining biocompatible materials is graft polymerisation. This method is most often used to produce hydrogels, mainly based on polyacrylamide, polyvinyl alcohol and polyethylene oxide.
The advantage of radiation cross-linking is comparative simplicity of execution, possibility of wide regulation of mesh density by selection of irradiation conditions (dose rate, dose), possibility of using reduced temperatures, purity of the obtained product (absence of initiators) and simultaneous sterilisation. Radiation-crosslinked hydrogels are used as carriers of biologically active substances (enzymes, drugs, etc.), as implants, prostheses, eye lenses, medical membranes, dressing materials and biological media for the study and cultivation of microorganisms.
The alteration of the physical properties of materials (mainly solids) as a result of irradiation has provided the basis for several other practical applications. They include ion implantation (at ion accelerators), doping of semiconductors by nuclear reactions (under the action of thermal neutrons), modification of semiconductor materials and products, fabrication of polymer membranes and resistors for lithography, changing the colour of glass and crystals, thermal effect of powerful electron beams, etc.